Health benefit
Muscle relaxant
Botanical Origin
Gloriosa superba L.
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PHARMACEUTICALS
Thiocolchicoside
crystallized from EtOH
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The Active Ingredient
Into the Plant
Botanical Origin
Gloriosa superba L.
Type
Pure Molecule
Plant source
Seed
Health benefit
Muscle relaxant
Assay
≥97.0% ≤102.0% by HPLC
Broad category
Muscle Relaxation
The natural relief for painful muscle stiffness or spasm
Thiocolchicoside, a skeletal-muscle-relaxant compound with anti-inflammatory and analgesic effects, is a derivative of colchicoside, a natural glucoside of the Gloriosa superba flower seeds. Thanks to its potent selective bind to the GABA-A receptor, it is used as an adjuvant product to treat painful muscle contractures, both in rheumatic and traumatic ones.
Thicolchicoside has a high affinity for GABA receptors, activating the GABA inhibitory pathways, and for glycine receptors leading to a muscle relaxant result. This is the reason why it is considered useful in alleviating Parkinson’s disease and iatrogenic Parkinson symptoms.
Furthermore, it could be used for acute and chronic lumbar and sciatic pain, persistent torticollis, cervico-brachial neuralgia, post-traumatic and post-operative pain.
