AIM AT INFLAMMATION
HIT MULTIPLE TARGETS, NATURALLY
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NUTRACEUTICALS
Quercefit®
Quercetin - Indena Phytosome®
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NEW SCIENTIFIC EVIDENCE
A NEW DEFINITION OF INFLAMMATION BALANCE1
Understanding inflammation is crucial to comprehending the causes of various diseases: the deeper scientific research delves into this area, the more remarkable results emerge. The latest study on Quercefit® has proven its beneficial impact in alleviating fatigue symptoms, enhancing sleep quality, and improving physical performance.1 All due to its ability to modulate NF-kB leveling and control COX and LOX activation and cytokine production in our body!
Explore the results
Overview
We’ve set the absolute advantage
Quercetin is a natural flavonoid compound widely found in vegetables, fruits and nuts. Quercefit®, in particular, is derived from the flower buds of Sophora japonica L.3 and shows an activity profile that can be best described as “pleiotropic”, due to its beneficial effects on several and diverse physiological processes.3
For example, in-vitro, in-vivo and human studies have reported that quercetin – the “queen” of flavonoids – exhibits positive influence on blood circulation, immunity, virus exposure protection, metabolism, eye health and, more recently, on contrasting fatigue.1,2,3
At cellular level, quercetin shows:
• Antioxidant activity, through the direct inactivation of free radicals, inhibition of lipid peroxidation and inhibition of free radicals producing enzymes.4
• Modulation activity on the most important cytokine cascades, leveling down NF-kB activation, controlling COX and LOX activation and cytokine production.4
• Immunomodulation activity hampering histamine release, promoting IFN-γ release and fighting IgE.5
Quercefit® is your Ticket to Ride anywhere, at any time.
Quercefit® into action
Let’s see how it works.
IMMUNITY HEALTH AND SENOLYTIC FUNCTION
The beneficial impact of quercetin on the cytokine cascade is widely acknowledged, and numerous clinical studies have demonstrated its potential as a valuable ally in rebalancing the physiological immune response in various settings.
In particular, the administration of Quercefit® has been shown to significantly improve the condition of individuals experiencing fatigue after physical exercise, where an unbalanced inflammatory response is a recognized etiological factor.1
In another study, Quercefit® proved helpful in maintaining immune system health and modulating cytokine cascades in subjects potentially exposed to Covid-19, precisely thanks to its senolytic function: its supplementation helps people maintain healthy condition in a Sars-CoV-2 infectious environment. While the standard precautionary measures and treatments defined by medical protocols cannot be replaced, the severity of symptoms often depends on the way the initial phases of the illness are faced.6
ALLERGIES
Quercefit® is a natural remedy during allergy season, promoting the wellbeing of sensitive and intolerant subjects in periods when allergens are abundant and widespread. A wish come true for all allergy-prone people.9
And its potential against allergies doesn’t end there: a recent study on mildly symptomatic individuals highlighted that Quercefit® significantly preserves eye and nose from discomforts and improves overall quality of life.10
EYE HEALTH
Quercetin supplementation, when delivered properly, may offer a way to preserve healthy ocular physiology in people experiencing allergic conjunctivitis, treated with continuous anti-allergy medications.11 Once again, the benefits of Quercefit® are tied to effective target delivery, provided by the unrivaled Indena Phytosome®.
Furthermore, a series of case studies has highlighted that the oral administration of Quercefit® during topical antibiotic therapy on ocular tissues, damaged by mechanical, thermal or chemical trauma, can support faster restoration. The faster the better, when it comes to eye health.3
PHYSICAL PERFORMANCE
In triathlon athletes using Quercefit®, study have pointed out an optimization of training and performance and a leveling in oxidative stress. Quercefit® is the right partner to support optimal physical performance and prompt recovery.12
Find out how Quercefit®
is one step beyond
Like it does for many other botanical extracts, Indena Phytosome® delivery system transforms quercetin’s potential into real advantages, effectively optimizing bioabsorption, compared to the barely bioabsorbable natural form.2
The pioneering Indena Phytosome® technology platform, specifically intended to facilitate the dissolution profile and pharmacokinetics of botanical extracts, makes Quercefit® stand out.
That’s why Quercefit® contributes to overall wellbeing in many ways. Better performance, faster recovery.2
See through science
Peer-reviewed science on Quercefit®
Here you can find more scientific evidence for your review.
ACCESS NOWBibliography
1 Rondanelli M.; et al.; Biomedicine & Pharmacotherapy 167 (2023): 115453.
1 2 Riva A. et al.; Eur J Drug Metab Pharmacokinet (2018).
3Mazzolani et al.; International Journal of Case Studies in Clinical Research (2022); Volume 6 Issue 3: 10-19.
4Liu, Chan-Min, et al.; Biochimica et Biophysica Acta (BBA)-General Subjects (2012); 1820.10: 1693-1703.
5 Mlcek, Jiri, et al.; Molecules (2016); 21.5: 623.
6Rondanelli M. et al.; Life (2022).
7 Di Pierro F. et al.; Int J Gen Med 14 (2021):2807-2816.
8 Di Pierro F. er al; Frontiers in Pharmacology (2023).
9 Cesarone, M. R., et al.; Minerva medica (2019).
10 Yamada, S. et al. European review for medical and pharmacological sciences (2022) 4331–4345.
11 Mazzolani et al.; Austin of allergy (2022).
12 Riva A. et al.; Minerva Medica (2018); 109(4): 285-9.
QUERCEFIT® at a glance
Why choose Quercefit®?
01.
Based on Indena Phytosome®, a natural and food-grade delivery system.
02.
Optimizes quercetin bioabsorption with dose linearity, proven to be up to 20-fold more bioavailable and effective at lower dosages, preserving its natural ingredient profile.
03.
Interactions with some common pharmacological therapies are undergoing further scrutiny, but present studies suggest no significant effects.
04.
Helps to rebalance inflammatory status.
05.
Effective against manifestations of fatigue syndrome.
06.
Some studies have shown a possible positive protective effect on subjects exposed to viral load (i.e. Covid-19).
07.
Provides the benefits of traditional quercetin in respiratory health.
08.
Supports optimal physical performance and prompt recovery.
09.
Shows evidence of activity in conditions characterized by abnormal oxidative stress and immune responses.
10.
Easy to formulate stand-alone, easy to combine with multi-component formulations and versatile in terms of formulation options.
11.
Promotes faster eye wellbeing restoration.
12.
Has a pleiotropic antioxidant effect.
13.
Can be an aid fighting allergy related disturbs, also at ocular level.
Technical Data
Common Name
Quercetin phospholipids
Botanical Origin
Sophora japonica L.
Type
Extract
Plant source
Flower buds
-
Health benefit
Antioxidant activity, Eye wellbeing restoration, Immunity, Physical performance, Support in healing corneal and conjunctival trauma, Wellbeing optimization in allergy prone , Balance inflammation
Patent & Trademark
Quercefit® is patented.
Quercefit is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject to Indena’s authorization and to the acceptance of the terms and conditions set out in the Trademark Usage Guidelines downloadable HERE.
Specifications
High quercetin bioabsorption, up to 20 times higher
Recommended dose and use
250 mg once or twice a day. Quercefit® may be used in a variety of supplement formulations.
Assay
≥34.0% ≤42.0% of quercetin by HPLC
Broad category
Immune health, Respiratory Health, Sports nutrition, Eye health, Allergies
These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.
QUERCEFIT® documents
News about Quercefit®
NEWS / 23 Feb 22
Quercetin Phytosome® vs COVID-19: one more scientific evidence
Indena presents its unique Phytosome formulation of quercetin derived from Sophora japonica L. The respiratory area is where its health benefits have been recently explored. 2 human studies showed very interesting results in maintaining wellbeing by sensitive or intolerant subjects.
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