HEALTHY CARDIOVASCULAR FUNCTION
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Go to sectionObtained from Vitis vinifera L. seeds, Leucoselect® Indena Phytosome® is a smart combination of standardized grape-seed extract and soy lecithin, with a high concentration of oligomeric proanthocyanidins (OPCs).
It is useful for the health of your cardiovascular system thanks to its antioxidant power.
Specifically designed for supporting normal heart function and protecting from oxidative stress related challenges, thanks to Indena Phytosome® delivery system, Leucoselect® is an innovative formulation that optimizes antioxidants’ bioabsorption.
Thanks to OPC’s antioxidant activity, Leucoselect® Indena Phytosome® has shown relevant biological activity in human studies, with a real positive effect on antioxidant capacity, in particular improving antioxidant capacity of plasma1,2 and protecting LDL from oxidation in heavy smokers3.
Furthermore, Leucoselect® Indena Phytosome® can affect positively oxidative status of people with impaired glucose homeostasis4 and life conditions and immune function of elderly people challenged by aging.5
The uniqueness of Leucoselect® Indena Phytosome® lies in its high content (80%) of smaller OPCs, critical for bioactivity since the absorption of procyanidins decreases with the oligomerization degree. Indeed, the extract is characterized by a very specific HPLC profile: it has a very high content of smaller OPCs and it is standardized to contain 25-36% of proanthocyanidins.
What’s more, the formulation with Indena Phytosome® strategy optimizes bioabsorption. Leucoselect® Indena Phytosome® is an optimal solution for an effective defense against oxidative damage, combining the efficacy of the antioxidant molecules and the innovative delivery system.
Bibliography
1Nuttal S. et al., J. Clin. Pharm.Ther. 23, 385 (1998).
2Natella F. et al., J. Agric. Food. Chem. 50, 7720 (2002).
3Vigna G. et al., Metabolism 52, 1250 (2003).
4Indena S.p.A., data on file.
5Magrone T. et al., Curr. Pharm. Des. 20:1011-9 (2014).
Is based on Indena Phytosome®, a natural and food-grade delivery system.
Has a high content (80%) of smaller OPCs.
Improves total antioxidant capacity of plasma.
Reduces LDL susceptibility to oxidative stress in heavy smokers.
Improves life conditions and immune function in elderly people challenged by aging.
Is easy to formulate as stand-alone, easy to combine with multi-component formulations and has versatile formulation options.
Common Name
Grape Seed extract phospholipids
Type
Extract
Plant source
Seed
Health benefit
Antioxidant capacity, Cardiovascular Health, Immune function support
Trademark
Leucoselect and Phytosome are trademarks of Indena S.p.A. The use of Indena’s trademarks is subject Indena’s authorization and to the acceptance of the terms and conditions set out in the Trademark Usage Guidelines downloadable HERE.
Specifications
High content (80%) of smaller size OPCs that are critical for bioactivity
Recommended dose and use
300 mg/day
Assay
25%-36% of proanthocyanidins (OPC) by GPC
Broad category
Antioxidant activity, Normal heart function
These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.
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