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Siliphos<sup>®</sup>
Siliphos<sup>®</sup>

NUTRACEUTICALS

Siliphos®

Silybin - Indena Phytosome®

The most advanced natural
liver health support

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Overview

We’ve set the absolute advantage

Silybum marianum (L.) Gaertn, better known as milk thistle, has been used for centuries to address liver health1. Its fruit contain complex flavonoids. Silybin, in particular, is the main flavanolignan constituent of silymarin, the fruit extract1, but unfortunately it has a poor intestinal bioabsorption that limits its benefit1,2.

Thanks to the Indena Phytosome® formulation, Siliphos® is the botanical derivative specifically developed to support liver health thanks its optimized silybin bioavailability and absorption3.

Extensive scientific data supports Siliphos® effectiveness in maintaining a healthy liver function, protecting it from oxidative stress4.

We’ve set the absolute advantage

Siliphos® into action

Siliphos® helps maintaining healthy liver function and can be used as a complementary approach to liver related challenges3,4.

And, what’s more, Siliphos® optimizes physiological insulin resistance and some liver markers in plasma3,5.

Siliphos<sup>®</sup> into action
Indena Phytosome®

Find out how Siliphos®
is one step beyond

The uniqueness of Siliphos® is radicated in its Indena Phytosome® strategy, a natural delivery system that overcomes and optimizes the poor bioavailability of silybin1,2.

Pioneering Indena Phytosome® formulation is specifically intended to facilitate dissolution profile and pharmacokinetic of botanical extracts, making Silipho so distinctive.

Find out more on Indena Phytosome®

See through science

Bibliography
1Morazzoni P. et al., Eur. J. Drug Metabol. Pharmacokinet. 17, 39 (1992).
2Morazzoni P. et al., Eur. J. Drug Metabol. Pharmacokinet. 18, 289 (1993).
3 Loquercio C. et al., Dig Dis Sci., 52(9): 2387-95 (2007).
4Vailati A. et al., Fitoterapia 64, 219 (1993).
5 Federico A. et al., Gut. 55(6): 901-902 (2006).

Siliphos® at a glance

Why choose Siliphos®?

01.

Is based on Indena Phytosome®, a natural and food-grade delivery system.

02.

Optimizes bioabsorption of silybin, the botanical extract constituent of milk thistle, preserving its natural ingredient profile.

03.

Is supported by numerous trials.

04.

Maintains healthy liver function, protecting it from oxidative stress.

05.

Can be used as a complementary approach to alleviate liver related challenges.

06.

Optimizes insulin resistance and other liver markers in plasma.

Technical Data

Common Name

Silybin phoshpolipids

Botanical Origin

Silybum marianum (L.) Gaertn.

Type

Extract

Plant source

Fruit

HALAL and KOSHER certified

Health benefit

Liver health, Protection from oxidative stress

Trademark

Siliphos is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject Indena’s authorization and to the acceptance of the terms and conditions set out in the Trademark Usage Guidelines downloadable HERE.

Specifications

High silybin bioabsorption

Recommended dose and use

Starting from 80 mg/day. SILIPHOS® may be utilized in a variety of nutraceutical formulations.

Assay

≥29.7% to ≤36.3% of silybin by HPLC

Broad category

Health Liver

These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.

SILIPHOS® documents

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