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NUTRACEUTICALS
Ubiqsome®
CoQ10 - Indena Phytosome™
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Overview
We’ve set the absolute advantage
Coenzyme Q10 (CoQ10) is a compound naturally produced by the body, essential for cellular energy and known for its antioxidant properties. However, its endogenous production tends to decline due to several internal and external factors.
Ageing is a primary cause: as we get older, CoQ10 biosynthesis slows down, contributing to reduced energy levels and increased oxidative stress. Certain medications, especially statins, can also interfere with its production.
Intense or prolonged physical activity raises mitochondrial energy demands and can accelerate CoQ10 consumption, especially when synthesis is already compromised.
Additionally, chronic illness, unbalanced diet, and psychological stress—can further impair the body’s ability to maintain adequate CoQ10 levels.
Recognizing these factors is key to understanding when CoQ10 support may be beneficial, especially with age, medication use, or a demanding lifestyle.
Thanks to its original Indena Phytosome™ formulation, Ubiqsome® reaches the right cellular concentration and – unlike any other supplements – can represent a valuable solution to help rebalance the body’s physiological production and demand for CoQ10.
Ubiqsome® in action
CARDIOVASCULAR OXIDATIVE STRESS PROTECTION1,2
Endothelial function is an important early marker for cardiovascular health, reflecting the ability of the endothelial layer to fight early pro-atherosclerosis conditions.
Since endothelial dysfunction is primarily driven by oxidative stress (like Reactive oxygen species - ROS and NO deficiency), the antioxidant potential of Ubiqsome® - CoQ10 Indena Phytosome™ could be a valuable ally to maintain the endothelium in good health, beyond any other available on the market.
A scientific evidence on healthy young people has confirmed this hypothesis, showing the optimization of endothelial function in both acute and chronic settings after the supplementation of Ubiqsome®.
MUSCULAR OXIDATIVE STRESS PROTECTION3,4
ROS are overproduced during intense training and exercise, contributing to muscular stress and damage.
A study on healthy, aging runners showed that the Ubiqsome® optimizes plasmatic and muscular CoQ10 concentration, counteracting oxidative stress right where it’s needed.
Another human study, focusing on cardiovascular health, showed Ubiqsome® also has beneficial effects on elderly people with statin-related asthenia.
What is the mechanism behind this evidence? Statins act by blocking the molecular pathway that leads to the synthesis of cholesterol, and in parallel also to the formation of CoQ10.
Ubiqsome® ensures optimal CoQ10 plasma levels even after just one dose, and shows an evident dose-dependent trend after a mere 2 weeks of supplementation.
Ubiqsome® emerges as the real game-changer in the field: thanks to its proprietary Indena Phytosome™ technology and proven via various scientific evidences, it delivers its core component to the intended target muscle cells, reaching the goal better and faster.
Indena Phytosome™
Find out how Ubiqsome®
is one step beyond
Ubiqsome® is the only CoQ10 formulation to benefit from Indena Phytosome™ delivery system, a strategy that optimizes the bioabsorption of this important cofactor.5
Outstanding clinical results have been accomplished, thanks to the innovative Indena Phytosome™ technology platform, also in enhancing one of CoQ10’s limiting factors: oral bioavailability and muscle cells uptake. The coenzyme’s high molecular weight and its very low aqueous solubility usually make it unsuitable for the oral administration route: that’s where the Indena Phytosome™ delivery system is particularly useful, improving and optimizing the uptake for more refractory cells and tissues.2,4
In addition, Ubiqsome® is the first CoQ10 formulation to have been tracked down to its real target, the inner space of cells where it is needed.
See through science
Peer-reviewed science on Ubiqsome®
Here you can find more scientific evidence for your review.
ACCESS NOWBibliography
1Marcheggiani F. et al.; Antioxidants; 12, 964 (2023).
2Cicero Afg. et al.; Biofactors.Sep;48(5):1160-1165 (2022).
3Drobnic F. et al.; J Food Sci Nutr Res 3 (4): 262-275 (2020);.
4Fogacci F, et al. J Clin Med. Jun 26;13(13):3741 (2024).
5Petrangolini G. et al.; Current Drug Delivery (2019).
UBIQSOME® at a glance
Why choose Ubiqsome®?
01.
Is the optimized delivery form of coenzyme Q10, formulated with Indena Phytosome™ technology.
02.
Supported by double-blind pharmacokinetic and human-efficacy studies.
03.
Optimizes CoQ10 plasma levels in a dose-dependent fashion and shows 14-fold higher solubility in simulated intestinal fluids.
04.
Optimizes CoQ10 levels in human muscle and epithelial cells.
05.
Is the first and only CoQ10 formulation on the market to have been tracked from oral administration down to its single, real target: the inner space of cells.
06.
Offers great potential for nutraceutical integration in any situation that requires an effective contribution of coenzyme Q10 for the wellbeing and balance of the body.
07.
Can be a cost-effective solution thanks to optimized bioabsorption – allowing for lower CoQ10 content without relying upon expensive capsulating technologies, as well as industrial scalability and versatile finished oral dosage forms.
08.
Supports the endothelial function’s ability to fight oxidation.
09.
Could be a promising ingredient for cardiovascular health, able to protect from cardiovascular risk factors.
10.
Protects muscle cells from statin-related adverse effects.
Technical Data
Common Name
CoQ10 phospholipids
Type
Ingredient with optimized bioabsorption
Plant source
-
Health benefit
Anti-ageing, Cellular energy support, Physical strength and performance, Senolytic, Skin Health
Patent & Trademark
Ubiqsome is patented (EP3307244).
Ubiqsome is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject to Indena’s authorization.
Specifications
Standardized to contain 18-22% of coenzyme Q10
Recommended dose and use
Up to 500 mg/day. Ubiqsome® may be used in a variety of supplement formulations.
Assay
18-22% of coenzyme Q10 by HPLC
Broad category
Weight loss companions, Beauty from within
These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.
UBIQSOME® documents
