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NUTRACEUTICALS
Quercefit®
Quercetin Indena Phytosome™
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Overview
We’ve set the absolute advantage
Quercetin is a natural flavonoid compound widely found in vegetables, fruits and nuts. Quercefit®, in particular, is derived from the flower buds of Sophora japonica L. and shows an activity profile that can be best described as “pleiotropic”, due to its beneficial effects on several and diverse physiological processes.
For example, over 10 human studies have reported that Quercefit® – with quercetin being the “queen” of flavonoids – exhibits positive influence on healthy inflammatory response and on contrasting fatigue, immunity and virus exposure protection and eye health, both in long term strategies and as a companion adjuvant to standard treatments. All these to support longevity in and out.
At cellular level, quercetin shows:
• Antioxidant activity, through the direct inactivation of free radicals, inhibition of lipid peroxidation and inhibition of free radicals producing enzymes.
• Modulation activity on the most important cytokine cascades, leveling down NF-kB activation, controlling COX and LOX activation and cytokine production.
• Immunomodulation activity hampering histamine release, promoting IFN-γ release and fighting IgE.
• Senolytic activity hampering histamine release, promoting IFN-γ release and fighting IgE.
Quercefit® is your Ticket to Ride anywhere, at any time.
Quercefit® into action
Quercefit® is formulated with the proprietary Indena PhytosomeTM technology, exploiting all the main benefits of quercetin: furthermore the pharmacokinetic showed a bioabsorption optimization up to 20 fold compared to the unformulated flavonol.1
Quercefit® reveals its full potential all year round.
Thanks to a favourable balance in inflammatory response, Quercefit® supports physical performance and endurance benefitting muscle function, recovery and ache relief.2,3
Quercetin's proven senolytic effect4 may play a key role in promoting healthier skin and slowing the aging process at a cellular level: this internal rejuvenation reflects on the outside, helping maintain a youthful, radiant appearance from the inside out.
Quercefit® is a natural aid during allergy season, helping sensitive individuals manage allergen exposure. Multiple studies confirm its ability to reduce eye and nasal discomfort and improve quality of life in mildly symptomatic subjects.5-7
Quercefit® supports immune balance by modulating the cytokine cascade: it helps maintain immune health in environments with virus exposure, potentially reducing symptom severity during early stages of infection.8-10
Quercefit® may support eye health in people with allergic conjunctivitis and optimizing the recovery time of ocular tissue.11-12
As an added confirmation on the ingredient safety, Quercefit® demonstrated no evidences of negative interactions during undergoing selected chronic therapies.13
Find out how Quercefit®
is one step beyond
Like it does for many other botanical extracts, Indena Phytosome™ delivery system transforms quercetin’s potential into real advantages, effectively optimizing bioabsorption, compared to the barely bioabsorbable natural form.1
The pioneering Indena Phytosome™ technology platform, specifically intended to facilitate the dissolution profile and pharmacokinetics of botanical extracts, makes Quercefit® stand out.
That’s why Quercefit® contributes to overall wellbeing in many ways. Better performance, faster recovery.
See through science
Peer-reviewed science on Quercefit®
Here you can find more scientific evidence for your review.
ACCESS NOWBibliography
1 Riva A. et al.; Eur J Drug Metab Pharmacokinet (2019): 44(2): 169-77.
2 Rondanelli M.; et al.; Biomedicine & Pharmacotherapy 167 (2023): 115453.
3 Riva A. et al.; Minerva Medica (2018); 109(4): 285-9.
4 Lee S., et al., Nature (2025): 638 (8052): E46.
5 Cesarone, M. R., et al.; Minerva medica (2019): 110(6): 524-9.
6 Belcaro G., et al., Esperienze Dermatol (2020): 22(1): 5-9.
7 Yamada, S. et al., Eur Rev Med Pharmacol Sci (2022): 26(12): 4331-45.
8 Di Pierro F. et al.; Int J Gen Med 14 (2021): 2807-16.
9 Di Pierro F. et al; Frontiers in Pharmacology (2023): 13(13): 1096853.
10 Rondanelli M. et al.; Life (2022): 12(1): 66.
11 Mazzolani et al.; Austin J allergy (2022): 8(1): 1042.
12 Riva A. et al.; Int J Clinical & Case (2022): 6(3): 10-9.
13 Riva, A., et al. Minerva cardioangiologica 67(1)2019: 79-83.
QUERCEFIT® at a glance
Why choose Quercefit®?
01.
Quercefit® is based on Indena Phytosome™ technology, a natural and food-grade delivery system.
02.
Quercefit® optimizes quercetin bioabsorption with dose linearity, proven to be up to 20-fold more bioabsorbible and effective at lower dosages.
03.
Quercefit® is supported by a no-interactions human study with common pharmacological therapies.
04.
Quercefit® supports an healthy inflammatory status.
05.
Quercefit® provides relief from chronic fatigue symptoms.
06.
Quercefit® has shown a possible positive protective effect on subjects exposed to viral load (i.e. Covid-19).
07.
Quercefit® offers all the benefits of traditional quercetin in respiratory health.
08.
Quercefit® contributes to optimal physical performance and prompt recovery.
09.
Quercefit® exploits a pleiotropic antioxidant and immunomodulator effects.
10.
Quercefit® is easy to formulate stand-alone, easy to combine with multi-component formulations and versatile in terms of formulation options.
11.
Quercefit® promotes faster eye wellbeing restoration.
12.
Quercefit® can be an aid in overcoming allergy related disturbs, also at ocular level.
Technical Data
Common Name
Quercetin phospholipids
Botanical Origin
Sophora japonica L.
Type
Extract
Plant source
Flower buds
Health benefit
Anti-ageing, Eye health, Healthy inflammatory response, Physical strength and performance, Senolytic, Skin Health, Wellbeing optimization in allergy prone
Patent & Trademark
Quercefit® is patented.
Quercefit is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject to Indena’s authorization,
Specifications
High quercetin bioabsorption, up to 20 times higher
Recommended dose and use
250 mg once or twice a day. Quercefit® may be used in a variety of supplement formulations.
Assay
≥34.0% ≤42.0% of quercetin by HPLC
Broad category
Chronic Ache Relief, Beauty from Within
These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.
QUERCEFIT® documents
News about Quercefit®
NEWS / 23 Feb 22
Quercetin Phytosome® vs COVID-19: one more scientific evidence
Indena presents its unique Phytosome formulation of quercetin derived from Sophora japonica L. The respiratory area is where its health benefits have been recently explored. 2 human studies showed very interesting results in maintaining wellbeing by sensitive or intolerant subjects.
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