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Enovita<sup>®</sup>
Enovita<sup>®</sup>

NUTRACEUTICALS

Enovita®

Grape seed extract

The natural ally for your blood pressure and mood

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ALL THE BENEFITS OF GROWING
HEALTH AND SUSTAINABILITY

Crafted from the essence of grape seeds mainly harvested from local vineyards, Enovita® not only embodies a natural approach to support optimal blood pressure and mood, but also proudly embraces sustainable and circular principles.

By promoting local sourcing, meticulous selection of raw materials, and innovative reuse of byproducts, Enovita® champions responsible production and contributes to the pursuit of good health and wellbeing, aiming to achieve the UN’s Sustainable Development Goals.

Sustainability and upcycling are the principles at Enovita®’s core, in every stage of production. By implementing responsible waste management, using renewable energy, leveraging a filtering system and applying best practices throughout all industrial processes, Indena is able to strike the balance between offering key products and safeguarding our planet’s natural resources.

ALL THE BENEFITS OF GROWING<br>HEALTH AND SUSTAINABILITY

Overview

We’ve set the absolute advantage

Balance is the key in everything, and especially in alcohol consumption. As part of a healthy lifestyle and moderate drinking pattern, red wine may have a beneficial effect against overall cardiac stress thanks to its phenolic constituents, which are mostly proanthocyanidins contained in grape seeds.1

Indeed, proanthocyanidins appear to be the best validated dietary substances to promote the maintenance of healthy blood pressure values1 and the resilience across life challenges – and Enovita® is a proprietary extract rich in proanthocyanidins (OPCs), made exclusively with grape seeds from white wine production.

And there’s more: Enovita® is poised to become an ally for both cardiovascular wellbeing and stress resilience.

We’ve set the absolute advantage

Health and Sustainability

LESS WASTE, LESS CARBON, MORE HEALTH
Enovita®’s commitment to sustainability begins with the first step in the supply chain: the use of grape seeds primarily sourced from Champagne and other French wine regions, located near Indena Tours’ s production site, reduces the carbon footprint while also bolstering the local economy. Moreover, Enovita® embraces the principles of circularity and upcycling, because the grape seeds used for extraction are essentially a byproduct of winemaking. And that’s not all: residual materials are also given a new life as they are transformed into seed oil for the food industry, steam from a biomass boiler, biogas suitable for energy generation, and fertilizers used to nurture the soil anew.

A PLANET-CENTRIC PRODUCTION SITE
Acknowledging responsibility towards the planet, Enovita® is produced at Indena Tours, a state-of-the-art facility in France where production practices are designed according to the “One Health” rule. To accomplish this, industrial processes harness power from an array of photovoltaic panels, leveraging solar energy to reduce the carbon footprint. With unwavering dedication to minimizing environmental impact, the production process is implemented with a comprehensive waste recovery system, ensuring that production byproducts find new life rather than burden the environment. Furthermore, the process uses an advanced dust filtration system to capture emissions, safeguarding air quality in the surroundings.

Health and Sustainability

Enovita® into action

Supported by scientific evidence, Enovita® is the natural solution to maintain blood pressure within a normal range, resulting in a positive leveling of both systolic and diastolic blood pressure values in people with higher cardiovascular risk with possible beneficial effects for all risk factors associated with heart stress1

Human studies showed that Enovita® is able to modulate blood pressure also in healthy and borderline subjects, thanks to a positive modulation of multiple parameters related to endothelial function demonstrated in preclinical tests (eNOS, Endothelin-1).2
The same study concluded that Enovita® is also effective in improving mood, stress management and quality of life, as well as in reducing perceived stress and worries.2

Beneficial effects on brain health were confirmed in a recent human study, where Enovita® revealed a statistical trend on mood modulation, related to anger item and emotional distress.3


In addition, Enovita® was effective in supporting working memory and in reducing errors in remembering short-term information that can lead to major errors in everyday calculations and decision-making.3

Enovita<sup>®</sup> into action

Find out how Enovita®
is one step beyond

Using only water as extraction solvent, Enovita® is a unique food-grade grape seed extract developed by capitalizing on Indena’s 40 years’ experience in the production of grape seed extracts.

Furthermore, Enovita®has a relatively low amount of flavane monomers, catechin and epicatechin (5.0-15.05%) and a high content of oligomeric proanthocyanidins determined with the Folin-Ciocalteu method.

Find out how Enovita<sup>®</sup> <br> is one step beyond

things to watch

Things to watch

Brain Health
Feed your mind, fill your life.

Your brain makes you uniquely you. As life's pace challenges our mental well-being, nature offers specific solution. Discover Indena's golden quartet of botanical ingredients, carefully selected to nurture your brain health and help you live life to its fullest.

HEALTH STORIES / 04 Nov 24
6.23
Brain Health <br /><strong><em>Feed your mind, fill your life.</em></strong>
Go to detail

See through science

Bibliography
1Belcaro G., Ledda A., Hu S., et al., Evidence-Based Complementary and Alternative Medicine, ID 313142 (2013).
2Schön C, et al. Nutrients. 13(2):654. (2021).
3Confidential data on file. Manuscript in preparation (2024).

 

ENOVITA® at a glance

Why choose Enovita®?

01.

Has a relatively low amount (5.0-15.05%) of flavane monomers (catechin and epicatechin), high oligomeric proanthocyanidin content, and a very specific gel permeation chromatography profile.

02.

Can maintain blood pressure within a normal range when associated with a healthy diet and lifestyle, supporting cardiovascular wellbeing.

03.

Promotes blood pressure regulation both in case of hypertension and in healthy or borderline subjects.

04.

Is naturally good for the mood, providing a positive effect on perceived stress and worries.

05.

Shows a high antioxidant activity.

06.

Decreases plasma oxidative status.

07.

Exemplifies sustainable and circular principles, such as the incorporation of locally sourced materials, the reuse of waste products and the use of solely water as an extraction solvent, together with the establishment of an environmentally conscious production site.

08.

Is produced according to the Indena Quality System under HACCP conditions in a GMP- and ISO-14001, ISO 45001 and FSSC 2200 certified facility. This last certification ensures full traceability from grape harvest to the finished product.

Technical Data

Common Name

Grape Seed standardized extract

Botanical Origin

Vitis vinifera L.

Type

Extract

Plant source

Seed

HALAL and KOSHER certified. COSMOS validated and GRAS affirmed

Health benefit

Antioxidant activity, Cardiovascular Health, Mood Modulator, Normal blood pressure

Trademark

Enovita is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject Indena’s authorization and to the acceptance of the terms and conditions set out in the Trademark Usage Guidelines downloadable HERE.

Specifications

High contents of oligomeric proanthocyanidins as determined with the Foli-Ciocalteu method

Recommended dose and use

2 x 150 mg/day. Enovita® may be utilized in a variety of nutraceutical formulations.

Assay

≥95.0% of proanthocyanidins by spectrophotometry
≥5.0% ≤15.0% of catechin and epicatechin by HPLC

Broad category

Antioxidant, Capillartropic, Stress Resilience

These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.

ENOVITA® documents

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