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Bilear<sup>®</sup>
Bilear<sup>®</sup>

NUTRACEUTICALS

Bilear®

Artichoke extract

Easy Digestion and Healthy Bile Flow

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Overview

We’ve set the absolute advantage

Since Roman times, artichoke leaves (Cynara cardunculus L. leaves) have been used in Europe as a traditional medicine with both choleretic and diuretic properties1.

A growing body of scientific evidence has then emerged and artichoke leaf extracts are nowadays sometimes used as a remedy for indigestion.2

Bilear®, Cynara cardunculus L. leaves extract, is a triple standardized dry extract with a specific phytochemical profile, whose efficacy is supported and proven by pharmacological and human studies.

We’ve set the absolute advantage

Bilear® into action

Artichoke leaf extracts exert effects on lipid metabolism as well as liver and gastrointestinal tract function1. They regulate bile production and flow from the liver to intestine.3

Recent studies provide evidence for artichoke leaf extracts effectiveness in conditions such as dyspepsia and irritable bowel syndrome.2,4

Bilear® works beneficially thanks to its specific formulation profile: a defined concentration of flavonoids, caffeoylquinic acid and chlorogenic acid.


Bilear<sup>®</sup> into action

Find out how Bilear®
is one step beyond

The uniqueness of Bilear® lies in its triple standardized formulation, empowering the effects of artichoke’s ingredients, as luteolin-7-O-glucoside and chlorogenic acid.

Plus, Bilear® is obtained from a specific artichoke variety particularly rich in active ingredients; the fine selection of raw ingredients is a guarantee of the final product quality.

Bilear® is produced according to EP 7.0 monograph.

Find out how Bilear<sup>®</sup><br>is one step beyond

See through science

Bibliography
1Walker, A.F., et al. Phytother Res, 15(1): p. 58-61 (2001).
2Bundy, R., et al., Phytomedicine, 15(9): p. 668 75 (2008).
3Kirchhoff, R., et al., Phytomedicine, 1(2): p. 107-15 (1994).
4Holtmann, G., et al., Aliment Pharmacol Ther, 18(11-12): p. 1099-105 (2003).

BILEAR® at a glance

Why choose Bilear®?

01.

Goes through a triple standardization process.

02.

Has a unique proven phytochemical profile.

03.

Helps maintaining a healthy gastrointestinal tract.

04.

Optimizes total plasma cholesterol.

05.

Reduces discomfort related to dyspepsia.

06.

Promotes healthy liver function.

Technical Data

Common Name

Artichoke standardized extract

Botanical Origin

Cynara cardunculus L.

Type

Extract

Plant source

Leaf

HALAL certified and CEP granted

Health benefit

Liver health, Gastrointestinal health, Healthy blood levels, Healthy cholesterol levels, Lipid metabolism

Trademark

Bilear® is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject to Indena’s authorization and to the acceptance of the terms and conditions set out in the Trademark Usage Guidelines downloadable HERE.

Specifications

Triple standardized, guaranteeing a unique formulation profile.

Recommended dose and use

≥320 mg a day. This is a light yellow-brown powder for use in nutraceutical supplements.

Assay

≥0.3% flavonoids expressed as luteolin-7-O-glucoside by HPLC
≥2.5% caffeoylquinic acid expressed as chlorogenic acid by HPLC
≥0.6% chlorogenic acid by HPLC

Broad category

Cholesterol and intestinal health

These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.

BILEAR® documents

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