HEALTHY PROSTATE AND BLADDER FUNCTION
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Go to sectionSerenoa repens, normally known as saw palmetto, is a low shrubby palm native to North America, where it grows in pine woods and among the sandy dunes in the coastal wetlands of South Carolina, Louisiana, Georgia and Florida. Its partially dried, ripe fruits have long been used in traditional American medicine to support healthy prostate and bladder function1.
Conditions related to prostatic stress are one of the most common medical challenges in older men2. Sabalselect® is a highly standardized S. repens extract that has proven efficacy in maintaining healthy prostate function and supporting healthy bladder activity2,3.
When trying to find a natural and well-tolerated ally to prostate and bladder health, Sabalselect ® is the way.
Extensively human studies underline Sabalselect® effective activity in supporting healthy prostate function.2,3
Several researches support a multiple mechanism of action of Sabalselect® activity on modulation of 5α-reductase5,6, double action on cycloxygenase and lipoxygenase7, levelling of chemotactic leukotriene production by cells8, attenuation of response of prostate cells to growth factors9, modulatory effect on nuclear estrogen receptors10, α-adrenoceptor antagonistic properties11 and interference with the action of prolactin12.
Available in 2 physical forms – liquid extract and 30% powder extract – Sabalselect® is safe and very well tolerated.3
The uniqueness of Sabalselect® is, no doubt, its highly standardized S. repens extract, obtained with a hypercritical CO2 process that defines a chemical profile with reproducible phytochemical characteristics.
What’s more, Sabalselect® is supported by a full toxicological package4.
Bibliography
1Duke J.A., “CRC - Handbook of Medicinal Herbs” 443 (1991).
2Braeckman J., Curr. Ther. Res. 55, 776 (1994).
3Braeckman J., Bruhwyler J., Vandekerchove K., Géczy J., Phytother. Res. 11, 558 (1997).
4Indena S.p.A., Internal Report 41/05/LRA-00.
5Hagenlocher M., Romalo G., Schweikert H.U., Akt. Urol. 24, 146 (1993).
6Bayne C.W., Grant E.S., Chapman K., Habib F.K., J. Urol. 157, 194 (1997).
7Breu W., Hagenlocher M., Redl K., Tittel G., Stadler F.,Wagner H., Arzneim. Forsch. 42, 547, (1992).
8Paubert-Braquet M., Mencia Huerta J.M., Cousse H., Braquet P.,Prostaglandins, Leukotrienes and Essential Fatty Acids 57, 299 (1997).
9Paubert-Braquet M., Cousse H., Raynaud J.P., Mencia Huerta J.M., Braquet P., Eur. Urol. 33, 340 (1998).
10Wilt T., Ishani A., Mac Donald R., The Cochrane Library, Issue 2 (2004).
11Odenthal K.P., Phytother. Res. 10, S141 (1996).
12Di Silverio F., D’ Eramo G., Lubrano C., Flammia G.P., Sciarra A., Palma E., Caponera M., Sciarra F., Eur. Urol. 21, 309 (1992).
Is effective for the relief of the urinary stresses associated with prostate health.
Is extracted with a hypercritical CO2 process and it has a defined chemical profile with reproducible phytochemical characteristics.
Is safe and supported by a full toxicological package.
Has been demonstrated to be very well tolerated and to greatly optimize the urodynamic parameters for supporting healthy bladder function in older males.
Is available in 2 physical forms with no significant differences: liquid extract and a 30% powder extract.
Common Name
Sabalselect® - Saw palmetto extract
Botanical Origin
Serenoa repens (Bartr.) Small
Type
Extract
Plant source
Fruit
KOSHER certified
Health benefit
Bladder function, Prostate function, Urinary stress relief
Trademark
Sabalselect is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject Indena’s authorization and to the acceptance of the terms and conditions set out in the Trademark Usage Guidelines downloadable HERE.
Specifications
Extracted with hypercritical CO2 process
Recommended dose and use
Up to 320 mg/day. Sabalselect® is available in 2 physical forms: liquid extract and a 30% powder extract
Assay
≥85.0% ≤95.0% of fatty acids
≥0.01% ≤0.15% of fatty alcohols
≥0.25% ≤0.50% of total sterols
≥0.15% ≤0.35% of β-sitosterol
Broad category
Healthy prostate and bladder function
These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.
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